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Inspiring Stories in Inclusion Body Myositis (sIBM)

March 16, 2018

Dr. Todd Cohen and the efforts of the Cohen Lab were mentioned in the Oshkosh Herald!  The story below features the efforts of Gary Beyer, a patient with sporadic Inclusion Body Myositis (sIBM), a muscle weakening disease that is similar in molecular origin to Amyotropic Lateral Sclerosis (ALS).

The article also mentions a Podcast Conversation with Dr. Todd Cohen on similar subjects

To read the full story, click the pdf link below!

 

Click here to download- Oshkosh Newsletter page 3

TDP-43 in Amyotrophic Lateral Sclerosis

June 22, 2017

 TDP-43 mediated neurodegeneration in Amyotrophic Lateral Sclerosis (ALS) 

Like tau acetylation and phosphorylation in Alzheimer’s Disease, TDP-43 modifications similarly promote aberrant pathology seen in diseased brain and spinal cord of ALS and FTLD-TDP patients. Understanding such post-translational mechanisms could lead to better therapeutic avenues to pursue for ALS, FTD and other diseases characterized by TDP-43 pathology.