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I received my PhD degree in Genetics from North Carolina State University in 2009 under the direction of Dr. Robert Anholt. My PhD thesis project was focused on the identification of genetic variation in odorant binding protein genes that affect variation in olfactory behavior in response to different odorants in a large natural Drosophila population. After completion of my PhD degree, I worked as a postdoc at NCI and Duke to study the mechanisms of human diseases. In 2014, I joined Dr. Cohen’s lab at the University of North Carolina, Chapel Hill. Currently, my research focuses on TDP-43 acetylation in neurodegenerative diseases and related TDP-43 proteinopathies, in particular, (1) dissecting the pathological mechanism of TDP-43 acetylation in sporadic inclusion body myositis (sIBM) using cell culture and in vivo skeletal muscle systems (see publication for this work: Wang et al. Nature Communications 2017); (2) determining how and to what extent TDP-43 acetylation alters the muscle transcriptome using RNA-seq approach. (3) developing FTLD/ALS mouse model.  During my spare time, I like Tabata workout, reading and cooking.

 

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